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编 号:F005584
分子式:C23H31ClN2
分子量:370.96
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Levemopamil hydrochloride is a blood-brain barrier penetrable calcium channel blocker and a 5-HT2 antagonist. Levemopamil hydrochloride can be used for temporary occlusion and neurological disease research.

体内研究:
Levemopamil hydrochloride (30 mg/kg;腹腔注射,1 次) 可调节双侧颈动脉阻尼 (BCCA) 过程,降低大鼠脑低血症引起的空间记忆障碍。Animal Model:Male Han-Wistar rats with bilateral damping of carotid arteries (BCCA)
Dosage:30 mg/kg
Administration:Intraperitoneal injection; 30 mg/kg, once
Result:Showed no effect on GABA or ACh content in either BCCA or sham-operated control rats. Significantly increased swimming speed of BCCA rats in swimming test. Prevented the increasing of escape latency to reach the hidden platform.
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