产品
编 号：F482557
分子式：C13H10N2O
分子量：210.23
分子式：C13H10N2O
分子量：210.23
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 85-66-5
产品详情
生物活性：
Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity.
体内研究：
Pyocyanin (intranasal, 50 μg/50 μL in 0.9% saline) 在 C57BL/6 J 小鼠体内诱导全身氧化应激、炎症和行为改变。Animal Model:C57BL/6 J mice
Dosage:50 μg/50 μL in 0.9% saline
Administration:intranasal
Result:Reduced the spontaneous locomotor activity.Increased in lipid peroxidation, and systemic inflammation.
体外研究：
Pyocyanin (5, 10 μM, 24 h) 对小鼠腹腔巨噬细胞具有抗炎作用，下调一氧化氮、TNF-α 和 IL-1β 水平。Pyocyanin (10, 20, 40 μg/mL, 48 h) 呈剂量依赖性的抑制 MRSA 的活性，MIC 值为8 μg/mL。
Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity.
体内研究：
Pyocyanin (intranasal, 50 μg/50 μL in 0.9% saline) 在 C57BL/6 J 小鼠体内诱导全身氧化应激、炎症和行为改变。Animal Model:C57BL/6 J mice
Dosage:50 μg/50 μL in 0.9% saline
Administration:intranasal
Result:Reduced the spontaneous locomotor activity.Increased in lipid peroxidation, and systemic inflammation.
体外研究：
Pyocyanin (5, 10 μM, 24 h) 对小鼠腹腔巨噬细胞具有抗炎作用，下调一氧化氮、TNF-α 和 IL-1β 水平。Pyocyanin (10, 20, 40 μg/mL, 48 h) 呈剂量依赖性的抑制 MRSA 的活性，MIC 值为8 μg/mL。
产品资料
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