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编 号:F058037
分子式:C16H16O3
分子量:256.3
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生物活性:
(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane is a homoisoflavonoid. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane increases the level of alkaline phosphatase (ALP) activity. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane promotes mesenchymal stem cells (MSCs) osteogenesis, but cannot enhance MSCs proliferation. (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane can be used for osteoporosis research.

体外研究:
(3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane (10 μM) 通过增加碱性磷酸酶 (ALP) 活性水平显著促进 MSCs 成骨分化。与对照组相比,早期成骨细胞分化率为162.0±1.4。
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