产品
编 号:F064966
分子式:C20H13N3O2
分子量:327.34
产品类型
结构图
CAS No: 119139-23-0
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产品详情
生物活性:
Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM.
体外研究:
Bisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC50 of 0.1 μM in 1 % DMSO, while the IC50 of 0.55 μM in 10 % DMSO.