产品
编 号：F715023
分子式：C19H23FN2O4S
分子量：394.46
分子式：C19H23FN2O4S
分子量：394.46
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规格
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CAS No: 2071636-15-0
产品详情
生物活性：
Lp-PLA2-IN-2 is a potent and selective lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.
体内研究：
Lp-PLA2-IN-2 (1 mg/kg; i.v.) treament in rats shows that the Cl, Vss and t1/2 values are 67 mL/min/kg, 1.2 L/kg, and 0.34 hours, respectively.Animal Model:Male Han Wistar rats (250-300 g)
Dosage:1 mg/kg
Administration:i.v. (Pharmacokinetic Analysis)
Result:The Cl, Vss and t1/2 values were 67 mL/min/kg, 1.2 L/kg, and 0.34 hours, respectively.
体外研究：
Lp-PLA2-IN-2 inhibits Human Lp-PLA2 with an IC50 of 62 nM in PED6 assay.
Lp-PLA2-IN-2 is a potent and selective lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.
体内研究：
Lp-PLA2-IN-2 (1 mg/kg; i.v.) treament in rats shows that the Cl, Vss and t1/2 values are 67 mL/min/kg, 1.2 L/kg, and 0.34 hours, respectively.Animal Model:Male Han Wistar rats (250-300 g)
Dosage:1 mg/kg
Administration:i.v. (Pharmacokinetic Analysis)
Result:The Cl, Vss and t1/2 values were 67 mL/min/kg, 1.2 L/kg, and 0.34 hours, respectively.
体外研究：
Lp-PLA2-IN-2 inhibits Human Lp-PLA2 with an IC50 of 62 nM in PED6 assay.
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