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编 号:F740647
分子式:C31H50O4
分子量:486.73
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Methyl maslinate is a β-adrenergic antagonist. Methyl maslinate is a potent cardiotonic and antidysrhythmic agent. Methyl maslinate has the potential for hypertension research.

体内研究:
Methyl maslinate (MM) (20-60 mg/kg; i.p.) shows significant, dose-dependent vasodepressor effect and sinus bradycardia, lasting more than 60 minutes with a maximum at 20 minutes, and shows potent hymodynamic effect.Methyl maslinate (40 mg/kg) shows antidysrhythmic activity on ischemia-reperfusion dysrhythmia.Animal Model:Wistar male rats (300-320 g)
Dosage:20-60 mg/kg
Administration:Intraperitoneal injection; once
Result:Showed significant, dose-response vasodepressor effect and sinus bradicardia.Antagonized β-Adrenergic.Showed antidysrhythmic activity.
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