产品
编 号：F741089
分子式：C16H15N5O2
分子量：309.32
分子式：C16H15N5O2
分子量：309.32
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CAS No: 1026587-58-5
产品详情
生物活性：
Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia.
体内研究：
Xanthine oxidoreductase-IN-4 (Compound IIIc) (oral; 5 mg/kg)在恶嗪酸钾/次黄嘌呤诱导的急性高尿酸血症模型中显示出显着的低尿酸血症效应。Animal Model:Mice acute hyperuricemia model
Dosage:5 mg/kg
Administration:Oral
Result:Reduced serum levels of uric acid significantly from 4 h after administration.
体外研究：
Xanthine oxidoreductase-IN-4 (Compound IIIc) 对 XOR 具有抑制活性，IC50 值为 29.3 nM。
Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia.
体内研究：
Xanthine oxidoreductase-IN-4 (Compound IIIc) (oral; 5 mg/kg)在恶嗪酸钾/次黄嘌呤诱导的急性高尿酸血症模型中显示出显着的低尿酸血症效应。Animal Model:Mice acute hyperuricemia model
Dosage:5 mg/kg
Administration:Oral
Result:Reduced serum levels of uric acid significantly from 4 h after administration.
体外研究：
Xanthine oxidoreductase-IN-4 (Compound IIIc) 对 XOR 具有抑制活性，IC50 值为 29.3 nM。
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