产品
编 号:F741256
分子式:C18H10F3N3O2
分子量:357.29
产品类型
结构图
CAS No: 1639929-29-5
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产品详情
生物活性:
Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs.
体外研究:
Chromenone 1 rescues DMH-1-induced cardiogenesis (IC50=0.2 μM) and efficiently stimulates BMP-dependent osteogenesis from C2C12 myoblasts.