产品
编 号：F741878
分子式：C43H70ClNO12
分子式：C43H70ClNO12
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CAS No: 1000802-56-1
产品详情
生物活性：
Pimecrolimus hydrate (SDZ-ASM 981 hydrate) is a potent, nonsteroid and orally active calcineurin inhibitor. Pimecrolimus hydrate shows anti-inflammatory activity. Pimecrolimus hydrate has the potential for the research of atopic dermatitis and oral erosive lichen planus.
体内研究：
Pimecrolimus hydrate (10, 30 mg/kg; p.o.; daily for 4 weeks) increases in absolute numbers of T lymphocytes in KLH-immunised rats compared with non-immunised animals.
体外研究：
Pimecrolimus hydrate (100 nM) targets T-cells and mast cells and inhibits the production and release of cytokines and other inflammatory mediators, as well as the expression of signals essential for the activation of inflammatory T-lymphocytes.
Pimecrolimus hydrate (SDZ-ASM 981 hydrate) is a potent, nonsteroid and orally active calcineurin inhibitor. Pimecrolimus hydrate shows anti-inflammatory activity. Pimecrolimus hydrate has the potential for the research of atopic dermatitis and oral erosive lichen planus.
体内研究：
Pimecrolimus hydrate (10, 30 mg/kg; p.o.; daily for 4 weeks) increases in absolute numbers of T lymphocytes in KLH-immunised rats compared with non-immunised animals.
体外研究：
Pimecrolimus hydrate (100 nM) targets T-cells and mast cells and inhibits the production and release of cytokines and other inflammatory mediators, as well as the expression of signals essential for the activation of inflammatory T-lymphocytes.
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