产品
编 号:F071047
分子式:C19H14F2N6O
分子量:380.35
产品类型
结构图
CAS No: 1207456-00-5
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产品详情
生物活性:
(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC50 of 144 nM.
体外研究:
(8R,9S)-Talazoparib shows an EC50 of 864 nM in cellular PARylation assay.(8R,9S)-Talazoparib shows an EC50 of 1135 nM for Capan-1 cells (BRCA2 mutant).