产品
编 号：F071495
分子式：C8H16O4
分子量：176.21
分子式：C8H16O4
分子量：176.21
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
3520
In-stock
100mg
3200
In-stock
1g
询价
询价
结构图
CAS No: 1208313-97-6
产品详情
生物活性：
Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes.
体内研究：
Ketone monoester 能够增加特定肌力，适度提高血糖浓度，降低 Aldh3b2 基因表达，增加血液 Na+ 水平和血肌酐水平，并降低血浆游离脂肪酸浓度。Animal Model:Septic mice
Dosage:10, 20, 40 and 80 mmol/kg/day
Administration:PO
Result:Increased specific muscle force as compared with placebo to 93% of healthy control levels at 40 mmol/kg/day.Resulted in moderately higher blood glucose concentrations as compared with placebo at 40 mmol/kg/day.Lowered Aldh3b2 gene expression than with placebo at 40 mmol/kg/day.Evoked a moderate further increase in blood Na+ levels and increased blood creatinine levels at 20 mmol/kg/day.Reduced plasma free fatty acid concentrations by 10 or 20 mmol/kg/day.Hepatic gene expression levels of Aldh1a7 was also reduced by sepsis but increased by D-3HHB.
Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes.
体内研究：
Ketone monoester 能够增加特定肌力，适度提高血糖浓度，降低 Aldh3b2 基因表达，增加血液 Na+ 水平和血肌酐水平，并降低血浆游离脂肪酸浓度。Animal Model:Septic mice
Dosage:10, 20, 40 and 80 mmol/kg/day
Administration:PO
Result:Increased specific muscle force as compared with placebo to 93% of healthy control levels at 40 mmol/kg/day.Resulted in moderately higher blood glucose concentrations as compared with placebo at 40 mmol/kg/day.Lowered Aldh3b2 gene expression than with placebo at 40 mmol/kg/day.Evoked a moderate further increase in blood Na+ levels and increased blood creatinine levels at 20 mmol/kg/day.Reduced plasma free fatty acid concentrations by 10 or 20 mmol/kg/day.Hepatic gene expression levels of Aldh1a7 was also reduced by sepsis but increased by D-3HHB.
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