产品
编 号:F743788
分子式:C23H23NO3
分子量:361.43
产品类型
结构图
CAS No: 128253-32-7
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产品详情
生物活性:
(S)-Veliflapon ((S)-BAY X 1005) is an orally active inhibitor of leukotriene biosynthesis and 5-lipoxygenase activating protein (FLAP). (S)-Veliflapon inhibits the formation of leukotriene B4 (LTB4) in rat, mouse and human leukocytes with IC50 values of 0.026 μM, 0.039 μM and 0.22 μM respectively. (S)-Veliflapon showes enantioselectivity in human whole blood.
体外研究:
(S)-Veliflapon 以剂量依赖性方式减少了人全血中白三烯 B4 (LTB4) 的合成。