产品
编 号:F075582
分子式:C17H19ClN2O4
分子量:350.8
产品类型
结构图
CAS No: 1215833-62-7
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产品详情
生物活性:
DMCM hydrochloride is a nonselective full inverse agonist of benzodiazepine. DMCM shows bnding afinity at human recombinant GABAA αxβ3γ2 receptor subtypes with Kis of 10 nM, 13 nM, 7.5 nM, 2.2 nM for α1, α2, α3, and α5 ?receptors, respectively.
体内研究:
DMCM has potent convulsant, proconvulsant and anxiogenic properties in vivo. DMCM (20-60 mg/kg; i.p.) produces modest anxiolytic-like effects in γ2I77 mice.Animal Model:Male γ2I77 mice
Dosage:20 mg/kg and 60 mg/kg
Administration:Injected i.p.
Result:Produced modest anxiolytic-like effects.