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编 号:F747350
分子式:C20H18N4O2
分子量:346.38
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5mg
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10mg
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生物活性:
BRD2492 (compound 6d) is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively. BRD2492 exhibits >100-fold selectivity for HDAC1/2 over selectivity over HDAC3 and HDAC6. BRD2492 inhibits breast cancer cell lines growth with IC50s of 1.01?μM and 11.13?μM for T-47D and MCF-7 cells, respectively.
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