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编 号：F748949
分子式：C25H32N6O4S
分子量：512.62
分子式：C25H32N6O4S
分子量：512.62
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CAS No: 2097499-67-5
产品详情
生物活性：
Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity.
体外研究：
Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC50=7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC50=18 μM; HT29 cells), PI3Ka (IC50=0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells.
Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity.
体外研究：
Antitumor agent-28 inhibits ataxia telangiectasia mutated (ATM; IC50=7.6 nM; HT29 cells), ataxia telangiectasia and Rad3-related protein (ATR; IC50=18 μM; HT29 cells), PI3Ka (IC50=0.24 μM; BT474 cells). Antitumor agent-28 does not inhibit mTOR in MDA-MB-468 cells.
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