产品
编 号：F751736
分子式：C30H28F2N2O6
分子量：550.55
分子式：C30H28F2N2O6
分子量：550.55
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CAS No: 2377724-93-9
产品详情
生物活性：
c-Met-IN-13 is a potent c-Met inhibitor with an IC50 value of 2.43 nM. c-Met-IN-13 shows excellent cytotoxicity for cancer cells. c-Met-IN-13 shows antiproliferative activity in a concentration- and time- dependent manner. c-Met-IN-13 has the potential for the research of cancer.
体外研究：
c-Met-IN-13 (compound 10m) shows cytotoxic activities with IC50s of 0.14, 0.20, 0.26 μM for H460, HT-29, MKN-45, respectively.c-Met-IN-13 shows tyrosine kinases selectively with IC50s of 4.42, 6.15, 18.64, 295, 540, >10000, 2.43 nM for c-kit, Flt-3,Ron, VEGFR-2, Flt-4, EGFR, C-Met, respectively.c-Met-IN-13 (0-300 μg/ml; 72 h) shows antiproliferative activity in a concentration and time dependent manner.
c-Met-IN-13 is a potent c-Met inhibitor with an IC50 value of 2.43 nM. c-Met-IN-13 shows excellent cytotoxicity for cancer cells. c-Met-IN-13 shows antiproliferative activity in a concentration- and time- dependent manner. c-Met-IN-13 has the potential for the research of cancer.
体外研究：
c-Met-IN-13 (compound 10m) shows cytotoxic activities with IC50s of 0.14, 0.20, 0.26 μM for H460, HT-29, MKN-45, respectively.c-Met-IN-13 shows tyrosine kinases selectively with IC50s of 4.42, 6.15, 18.64, 295, 540, >10000, 2.43 nM for c-kit, Flt-3,Ron, VEGFR-2, Flt-4, EGFR, C-Met, respectively.c-Met-IN-13 (0-300 μg/ml; 72 h) shows antiproliferative activity in a concentration and time dependent manner.
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