产品
编 号：F751847
分子式：C49H59N7O7S
分子量：890.1
分子式：C49H59N7O7S
分子量：890.1
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 2383086-06-2
产品详情
生物活性：
Sonrotoclax is a potent, orally active Bcl2 inhibitor. Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines.
体内研究：
Sonrotoclax (compound 1; 5-50 mg/kg; p.o.; 每日一次, 持续 42 天; 患有急性淋巴细胞白血病 (ALL) 异种移植物的雌性 NCG 小鼠) 具有抗肿瘤活性并抑制肿瘤生长。Animal Model:Female NCG mice with acute lymphoblastic leukemia (ALL) xenografts
Dosage:5, 15, 50 mg/kg
Administration:oral administration; daily, for 42 days
Result:Inhibited tumor growth in a dose-dependent manner.
Sonrotoclax is a potent, orally active Bcl2 inhibitor. Sonrotoclax has effective cell killing effect against a variety of lymphoma and leukemia cell lines.
体内研究：
Sonrotoclax (compound 1; 5-50 mg/kg; p.o.; 每日一次, 持续 42 天; 患有急性淋巴细胞白血病 (ALL) 异种移植物的雌性 NCG 小鼠) 具有抗肿瘤活性并抑制肿瘤生长。Animal Model:Female NCG mice with acute lymphoblastic leukemia (ALL) xenografts
Dosage:5, 15, 50 mg/kg
Administration:oral administration; daily, for 42 days
Result:Inhibited tumor growth in a dose-dependent manner.
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