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编 号：F751995
分子式：C66H112N20O21
分子量：2390.73
分子式：C66H112N20O21
分子量：2390.73
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CAS No: 239480-61-6
产品详情
生物活性：
NBI-6024, an altered peptide ligand (APL), is an epitope recognized by inflammatory interferon-gamma-producing T helper lymphocytes in type 1 diabetic patients.
体内研究：
NBI-6024 (0.005-20 mg/kg, s.c.) delays the onset and reduces the incidence of diabetes in mice.Animal Model:Nonobese diabetic (NOD) mice
Dosage:0.005, 0.05, 0.5, 5, 10, 20 mg/kg
Administration:Subcutaneous injection (s.c.)
Result:Observed dose-dependent induction of responsiveness to the immunizing antigen at 5, 10, 20 mg/kg (tested by culturing spleen cells pooled from mice).
NBI-6024, an altered peptide ligand (APL), is an epitope recognized by inflammatory interferon-gamma-producing T helper lymphocytes in type 1 diabetic patients.
体内研究：
NBI-6024 (0.005-20 mg/kg, s.c.) delays the onset and reduces the incidence of diabetes in mice.Animal Model:Nonobese diabetic (NOD) mice
Dosage:0.005, 0.05, 0.5, 5, 10, 20 mg/kg
Administration:Subcutaneous injection (s.c.)
Result:Observed dose-dependent induction of responsiveness to the immunizing antigen at 5, 10, 20 mg/kg (tested by culturing spleen cells pooled from mice).
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