产品
编 号:F752067
分子式:C25H23FN6O2
分子量:458.49
产品类型
结构图
CAS No: 2406276-78-4
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产品详情
生物活性:
OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM).
体外研究:
OM-153 shows inhibition (IC50=19 nM) in a cellular (HEK293) WNT/β-catenin signaling reporter assay.