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编 号:F752321
分子式:C20H18N3Na2O8PS
分子量:537.39
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生物活性:
Anticancer agent 62 (compound 4c) is a potent anticancer agent. Anticancer agent 62 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 0.019, 0.060 and 0.016 μM, respectively. Anticancer agent 62 shows effective tumor growth inhibition.

体内研究:
Anticancer agent 62 (compound 4c) (BALB/c mice, 0-50 mg/kg, IP, once) inhibits human HepG2 xenograft mouse tumor growth by 71.7% at 25 mg/kg.
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