产品
编 号：F752345
分子式：C29H24ClN7S3
分子量：602.2
分子式：C29H24ClN7S3
分子量：602.2
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规格
价格
是否有货
结构图
CAS No: 2413565-17-8
产品详情
生物活性：
COX-2-IN-27 is a potent and selective COX-2 inhibitor with IC50 values of 13.22, 0.045, 1.67 μM for COX-1, COX-2, 15-LOX, respectively. COX-2-IN-27 shows anti-inflammatory activity.
体内研究：
COX-2-IN-27 (28 μM/kg) shows a potent anti-inflammatory activity in rats with edema inhibition relative to indomethacin of 93.20% and 109.08% in 4h and 3h, respectively.
体外研究：
COX-2-IN-27 (compound 15b) shows significant COX-2 selectivity with an SI value of 293.78.
COX-2-IN-27 is a potent and selective COX-2 inhibitor with IC50 values of 13.22, 0.045, 1.67 μM for COX-1, COX-2, 15-LOX, respectively. COX-2-IN-27 shows anti-inflammatory activity.
体内研究：
COX-2-IN-27 (28 μM/kg) shows a potent anti-inflammatory activity in rats with edema inhibition relative to indomethacin of 93.20% and 109.08% in 4h and 3h, respectively.
体外研究：
COX-2-IN-27 (compound 15b) shows significant COX-2 selectivity with an SI value of 293.78.
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