产品
编 号:F752535
分子式:C21H19F5N6O4S
分子量:546.47
产品类型
结构图
CAS No: 2417228-90-9
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产品详情
生物活性:
Aurora kinase inhibitor-10 (Compound 6c) is an orally active Aurora B inhibitor with an IC50 of 8 nM. Aurora kinase inhibitor-10 shows antitumor activity.
体外研究:
Aurora kinase inhibitor-10 (Compound 6c) shows antiproliferation activity with IC50 values of 0.57 ± 0.23, 0.42 ± 0.20, 0.69 ± 0.30, 3.97 ± 0.67 and 1.53 ± 0.52 μM against MCF-7, MDA-MB 231, SkoV3, A375 and A549, respectively.