产品
编 号：F752707
分子式：C18H12N4O3S2
分子量：396.44
分子式：C18H12N4O3S2
分子量：396.44
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CAS No: 2432825-93-7
产品详情
生物活性：
HDAC8-IN-3 (compound P19) is a potent HDAC8 inhibitor with IC50 value of 9.3 μM and produces thermal stabilization. HDAC8-IN-3 has cytotoxicity and induces apoptosis in leukemic cell lines.
体外研究：
HDAC8-IN-3 (compound P19) (5-200 μM, 48 hours; HEK293T cells) has cytotoxicity in leukemic cell lines.HDAC8-IN-3 (compound P19) (50 μM) inhibits glucose transporter 1 (GLUT1)-mediated glucose transport by down-regulating GLUT1 expression (IC50 = 28.2 μM).HDAC8-IN-3 (compound P19) (79.9 μM; 24 hours) can induce apoptotic death in the CEM cell line.
HDAC8-IN-3 (compound P19) is a potent HDAC8 inhibitor with IC50 value of 9.3 μM and produces thermal stabilization. HDAC8-IN-3 has cytotoxicity and induces apoptosis in leukemic cell lines.
体外研究：
HDAC8-IN-3 (compound P19) (5-200 μM, 48 hours; HEK293T cells) has cytotoxicity in leukemic cell lines.HDAC8-IN-3 (compound P19) (50 μM) inhibits glucose transporter 1 (GLUT1)-mediated glucose transport by down-regulating GLUT1 expression (IC50 = 28.2 μM).HDAC8-IN-3 (compound P19) (79.9 μM; 24 hours) can induce apoptotic death in the CEM cell line.
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