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编 号：F753251
分子式：C23H19FN4O
分子量：386.42
分子式：C23H19FN4O
分子量：386.42
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CAS No: 2485135-31-5
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生物活性：
Topoisomerase I inhibitor 4 (compound 7a) is a topoisomerase I inhibitor. Topoisomerase I inhibitor 4 inhibits HepG2, A549, MCF-7 and HeLa cancer cells proliferation with IC50s of 1.20, 2.09, 1.56 and 1.92 μM, respectively. Topoisomerase I inhibitor 4 can be used for the research of cancer.
体外研究：
Topoisomerase I inhibitor 4 (1-80 μM) shows Top1 inhibitory activity.Topoisomerase I inhibitor 4 (0-40 μM; 48 h) inhibits proliferation of cancer cells.
Topoisomerase I inhibitor 4 (compound 7a) is a topoisomerase I inhibitor. Topoisomerase I inhibitor 4 inhibits HepG2, A549, MCF-7 and HeLa cancer cells proliferation with IC50s of 1.20, 2.09, 1.56 and 1.92 μM, respectively. Topoisomerase I inhibitor 4 can be used for the research of cancer.
体外研究：
Topoisomerase I inhibitor 4 (1-80 μM) shows Top1 inhibitory activity.Topoisomerase I inhibitor 4 (0-40 μM; 48 h) inhibits proliferation of cancer cells.
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