产品
编 号:F753346
分子式:C18H23N3O3
分子量:329.39
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5mg
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10mg
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25mg
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生物活性:
DKFZ-748 is a selective HDAC10 inhibitor (pIC50=7.66), and shows anti-tumor activity.

体外研究:
DKFZ-748 shows dose-dependent growth inhibition of HeLa cells in a polyamine-limiting in vitro tumor model.DKFZ-748 (1-100 μM; 72 h) induces HDAC acetylation of BE(2)-C cells.DKFZ 748 shows significant accumulation of N8 acetyl- and N1,8-diacetylspermidine in a dose-dependent manner.
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