产品
编 号:F753767
分子式:C20H30N4O7
分子量:438.47
产品类型
结构图
CAS No: 2566404-73-5
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产品详情
生物活性:
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
体外研究:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.