产品
编 号:F754029
分子式:C18H18ClF3N4O2
分子量:414.81
产品类型
结构图
CAS No: 260553-24-0
联系客服
产品详情
生物活性:
RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4–TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively.
体内研究:
RBP4配体
体外研究:
Retinol-Binding Protein 4 (RBP4) is a physiological carrier of retinol (vitamin A) in blood, delivering retinol from the liver to peripheral tissues.RBP4 ligand-1 has the ability todisrupt the RBP4–TTR protein–protein interaction (hRPB4–TTR). The RBP4–TTR FRET IC50 is0.13±0.12 μM in FRET assay.