产品
编 号:F754237
分子式:C25H29ClF2N6O2
分子量:518.99
产品类型
结构图
CAS No: 2641054-59-1
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产品详情
生物活性:
LRRK2-IN-4 is a potent, selective, CNS-penetran and orally active leucine-rich repeat kinase 2 (LRRK2) inhobitor with an IC50 of 2.6 nM. LRRK2-IN-4 has the potential for the research of Parkinson’s disease.
体内研究:
LRRK2-IN-4 (compound 24) (p.o.) shows good oral bioavailability in male Wistar-Han rats (F=64%), male beagle dogs (F=65%).