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编 号:F754496
分子式:C49H65N7O7S
分子量:896.15
产品类型
结构图
CAS No: 2669785-84-4
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JPS035 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS035 degrades class I histone deacetylase (HDAC). JPS035 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells.