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编 号:F754868
分子式:C25H24N6O
分子量:424.5
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CAS No: 2713577-16-1
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SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo.