产品
编 号:F755337
分子式:C26H25BrN4O3
分子量:521.41
产品类型
结构图
CAS No: 2750413-99-9
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产品详情
生物活性:
CCG-273463 is a potent, selective and covalent GRK5 inhibitor with an IC50 value of 8.6 nM. CCG-273463 can be used in the research of heart failure, hypertrophic cardiomyopathy, and cancer.
体外研究:
CCG-273463 (0.02-1 μM) potently and highly inhibits GRK5 (IC50: 8.6 nM), with inhibitory rate of 93% (GRK5) and 97% (GRK6) at 1 μM.