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编 号:F756100
分子式:C35H34N4
分子量:510.67
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生物活性:
AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER).

体外研究:
AIE-Cbz-LD-C (0, 2, 5, 10, 20, and 30 μM; 24 h) have excellent biocompatibility.AIECbz-LD-C7 (0.5 μM, 15 min) could aggregate in LDs accurately and light up the LDs with good photostability.AIE-Cbz-LD-C7 (0.5 μM) can be used to visualize the interplay between LDs and lysosomes during lipophag due to the excellent LD-specificity.AIE-Cbz-LD-C7 (0.5 μM, 15 min) increases the number of ferroptosis.
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