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编 号:F756237
分子式:C23H20Cl2N4O3
分子量:471.34
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生物活性:
DS01080522 is a Protein Kinase cAMP-Activated Catalytic Subunit Alpha (PRKACA) inhibitor. DS01080522 inhibits PRKACA kinase activity and CREB phosphorylation with IC50s of 0.8 nM and 66 nM, respectively. DS01080522 can be used for the research of cancer.

体外研究:
DS01080522 (1-10 μM; 30 min) affects phosphorylation of CREB.
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