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编 号:F756288
分子式:C15H15NO3
分子量:257.28
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生物活性:
Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC50=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC50=3.5 μM).

体外研究:
Anti-infective agent 6 (compound 28) is less cytotoxic with a CC50 value higher than 100 μM in macrophage RAW 264.7 cells and consequently a SI higher than 28 for Leishmania parasites.
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