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编 号：F756678
分子式：C21H19F2N3O6S
分子量：479.45
分子式：C21H19F2N3O6S
分子量：479.45
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CAS No: 2892432-98-1
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生物活性：
IDO1-IN-21 (compound 10m) is an IDO1 inhibitor (IC50 = 0.64 μM). IDO1-IN-21 effectively inhibits tumor growth in mice.
体内研究：
IDO1-IN-21 (50, 100 mg/kg; i.p.; every three day for 21 consecutive days) 抑制 CT26 荷瘤小鼠的肿瘤生长。Animal Model:CT26 tumor-bearing mice.
Dosage:50, 100 mg/kg
Administration:Intraperitoneal administration; every three day for 21 consecutive days.
Result:Led to significant suppression of tumor growth.
体外研究：
IDO1-IN-21 (0-50 μM; 48 h) 抑制 SW480 细胞活力，其 IC50 值为 28.64 μM。IDO1-IN-21 (0-10 μM; 48 h) 抑制 HeLa 细胞的 IDO1，其 IC50 值为 1.04 μM。
IDO1-IN-21 (compound 10m) is an IDO1 inhibitor (IC50 = 0.64 μM). IDO1-IN-21 effectively inhibits tumor growth in mice.
体内研究：
IDO1-IN-21 (50, 100 mg/kg; i.p.; every three day for 21 consecutive days) 抑制 CT26 荷瘤小鼠的肿瘤生长。Animal Model:CT26 tumor-bearing mice.
Dosage:50, 100 mg/kg
Administration:Intraperitoneal administration; every three day for 21 consecutive days.
Result:Led to significant suppression of tumor growth.
体外研究：
IDO1-IN-21 (0-50 μM; 48 h) 抑制 SW480 细胞活力，其 IC50 值为 28.64 μM。IDO1-IN-21 (0-10 μM; 48 h) 抑制 HeLa 细胞的 IDO1，其 IC50 值为 1.04 μM。
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