产品
编 号：F081154
分子式：C134H207N41O36S
分子量：3000.4
分子式：C134H207N41O36S
分子量：3000.4
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 122341-40-6
产品详情
生物活性：
Neuropeptide Y (13-36), amide, human is a selective?neuropeptide Y2 receptor?agonist.
体内研究：
Neuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol)produces a dose-dependent increase (up to 14%; ED50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat.Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into na?ve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y2 receptor antagonist BIIE 0246.Animal Model:Male ICR mice (age 4-7 weeks)
Dosage:50 ng/mouse
Administration:Intracerebroventricular injection
Result:Significantly decreased interaction time with the new stranger mouse in session 3 that NPY 13-36.
Neuropeptide Y (13-36), amide, human is a selective?neuropeptide Y2 receptor?agonist.
体内研究：
Neuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol)produces a dose-dependent increase (up to 14%; ED50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat.Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into na?ve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y2 receptor antagonist BIIE 0246.Animal Model:Male ICR mice (age 4-7 weeks)
Dosage:50 ng/mouse
Administration:Intracerebroventricular injection
Result:Significantly decreased interaction time with the new stranger mouse in session 3 that NPY 13-36.
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