产品
编 号:F757044
分子式:C16H15NO3S2
分子量:333.43
产品类型
结构图
CAS No: 2937819-61-7
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产品详情
生物活性:
TP-TRFS is a highly selective and the first two-photon fluorescent probe of thioredoxin reductase (TrxR).
体内研究:
TP-TRFS has the ability to visualize the TrxR activity in vivo, and also provides a mechanistic link between stroke and the loss of TrxR function, which may open up a new therapeutic window of stroke via the regulation of TrxR function.
体外研究:
TP-TRFS (10 μM) exhibits weak fluorescence (Φ = 0.57%, absolute quantum yield), and after TP-TRFS (10 μM)) is incubated with TCEP (1 mM), a dramatic fluorescence increment at 490 nm is observed (Φ= 22.31%, absolute quantum yield) and the fluorescence intensity of the test system increased by B40-fold within 3 h.