产品
编 号：F757515
分子式：C30H23N5O4
分子量：517.53
分子式：C30H23N5O4
分子量：517.53
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CAS No: 329706-62-9
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生物活性：
AG6033 is a potential novel CRBN modulator. AG6033 suppresses various tumor cells by modulating the interactions between CRBN and various antitumor target proteins. AG6033 can cause GSPT1 and IKZF1 degradation. AG6033 induces CRBN-dependent cytotoxic effect.
体外研究：
AG6033 (0.064-40 μM, 4 h) has potent inhibition ability against A549.AG6033 (1-10 μM, 24 h) significantly promotes apoptosis of A549 cells in a dose-dependent manner.
AG6033 is a potential novel CRBN modulator. AG6033 suppresses various tumor cells by modulating the interactions between CRBN and various antitumor target proteins. AG6033 can cause GSPT1 and IKZF1 degradation. AG6033 induces CRBN-dependent cytotoxic effect.
体外研究：
AG6033 (0.064-40 μM, 4 h) has potent inhibition ability against A549.AG6033 (1-10 μM, 24 h) significantly promotes apoptosis of A549 cells in a dose-dependent manner.
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