产品
编 号:F082121
分子式:C16H14O4
分子量:270.28
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10mM*1mL in DMSO
询价
询价
500mg
320
In-stock
1g
440
In-stock
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生物活性:
4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM.

体外研究:
By reducing irinotecaninduced diarrhea, hiCE inhibitors (e.g., 4,4'-Dimethoxybenzil, Compound 8) can improve the anti-cancer efficacy of irinotecan. To find effective hiCE inhibitors, a new virtual screening protocol that combines pharmacophore models derived from the hiCE structure and its ligands has been proposed.
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