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编 号:F758911
分子式:C10H7F3N6
分子量:268.2
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
PCAF-IN-2 (compound 17) is a potent PCAF inhibitor with an IC50 value of 5.31 μM. PCAF-IN-2 shows anti-tumour activity. CAF-IN-2 induces apoptosis and arrest the cell cycle at the G2/M phase.

体外研究:
PCAF-IN-2 shows anti-tumour activity with IC50s of 3.06, 5.69, 7.56, 2.83 μM for HePG2, MCF-7, PC3, HCT-116 cells, respectively.PCAF-IN-2 (10 μM; 24 h) induces apoptosis and arrest the cell cycle at the G2/M phase in HePG2 cells.
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