产品
编 号：F759471
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 652153-01-0
产品详情
生物活性：
Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody targets CD4. Zanolimumab effectively inhibits T-cell receptor (TCR) signal transduction. Zanolimumab can be used for the research of heumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.
体外研究：
Zanolimumab (10 and 100 ng/mL) shows strong killing of the CD4+ T cells with a better effect to CD45RO+ subset than the CD45RA+ subset.Zanolimumab (1-10000 ng/mL) Fc and dose-dependently down-regulates the level of CD4 from purified primary CD4+ T cells and SUP-T1 T cells. Zanolimumab (1-10000 ng/mL) potently inhibits of TCR-stimulated T-cell proliferation both in tetanus toxin induced and anti-CD3 induced T-cell proliferation. Zanolimumab (0-30 min) inhibits TCR signal transduction.
Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody targets CD4. Zanolimumab effectively inhibits T-cell receptor (TCR) signal transduction. Zanolimumab can be used for the research of heumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.
体外研究：
Zanolimumab (10 and 100 ng/mL) shows strong killing of the CD4+ T cells with a better effect to CD45RO+ subset than the CD45RA+ subset.Zanolimumab (1-10000 ng/mL) Fc and dose-dependently down-regulates the level of CD4 from purified primary CD4+ T cells and SUP-T1 T cells. Zanolimumab (1-10000 ng/mL) potently inhibits of TCR-stimulated T-cell proliferation both in tetanus toxin induced and anti-CD3 induced T-cell proliferation. Zanolimumab (0-30 min) inhibits TCR signal transduction.
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