产品
编 号:F763046
分子式:C16H20Cl2N8O2S
分子量:459.35
产品类型
结构图
CAS No: 2815778-41-5
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产品详情
生物活性:
Zalunfiban (RUC-4) dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban dihydrochloride can be used for the research of myocardial infarction (MI).
体内研究:
Zalunfiban dihydrochloride (1~3.86 mg/kg; s.c.; 24 hours) makes platelet aggregation performed.Zalunfiban dihydrochloride (1~3.86 mg/kg; i.m.; 4.5 hours) leads to the onset of high-grade inhibition of platelet aggregation within 15–30 minutes that lasts from ~2 to >4.5 hours in a dose dependent manner.Animal Model:Cynomolgus Monkey
Dosage:1~ 3.86 mg/kg (Pharmacokinetic Analysis)
Administration:S.c.; 24 hours
Result:Platelet aggregation was performed.