生物活性：
Ramucirumab (anti-VEGFR) is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab (anti-VEGFR) is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab (anti-VEGFR) is also an angiogenesis inhibitor.

体内活性：
Ramucirumab (10 μg/mL) 阻碍 VEGF 和肿瘤驱动的索形成。 Ramucirumab 不与小鼠 VEGFR2 发生交叉反应。

体外活性：
Ramucirumab (10 μg/mL) 阻碍 VEGF 和肿瘤驱动的索形成。 Ramucirumab 不与小鼠 VEGFR2 发生交叉反应。