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编 号:F088238
分子式:C10H15N5O3
分子量:253.26
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity.

体外研究:
Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys.Omaciclovir shows antiviral activities against different human herpesviruses with EC50s of 0.72?±?0.1, 0.62?±?0.2, 0.015?±?0.004,0.048?±?0.023, 0.047?±?0.004, 0.035?±?0.022, and 0.016?±?0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively.
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