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编 号:F112089
分子式:C14H8O3
分子量:224.21
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10mM*1mL in DMSO
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500mg
400
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生物活性:
1-Hydroxyanthraquinone, a naturally occurring compound with oral activity from some plants like Tabebuia avellanedae, exhibits carcinogenic effect.

体内研究:
1-Hydroxyanthraquinone (HA) generates strong DNA repair response and is carcinogenic in rats.Animal Model:Thirty rats.
Dosage:1% HA in diet.
Administration:Diet.
Result:Associated with decreased weight gain which was particularly marked towards the termination of experiment.One of the 30 rats in group 1 (experimental group) died of pneumonia 243 days after the start of experiment. A second rat died in an unnourished state at day 280, demonstrating a large tumor in the colon.Seven animals of the group died spontaneously or were sacrificed upon becomingmoribund between 335 and 462 days. A total of 21 rats of group 1 survived until the end of experiment (mean value of totalintake of HA/rat was 76.8 g).
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