产品
编 号：F113022
分子式：C9H6ClNO
分子量：179.6
分子式：C9H6ClNO
分子量：179.6
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
100
In-stock
5g
160
In-stock
结构图
CAS No: 130-16-5
产品详情
生物活性：
Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ.
体内研究：
Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
体外研究：
Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis.Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.
Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ.
体内研究：
Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
体外研究：
Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis.Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.
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