产品
编 号:F117103
分子式:C72H104N20O16S
分子量:1537.79
产品类型
结构图
CAS No: 131334-43-5
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产品详情
生物活性:
PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE).
体内研究:
PLP (139-151) 可用于动物建模,构建自身免疫性脑脊髓炎模型。
体外研究:
Severe clinical and histological EAE could be induced by adoptive transfer of the peptide-specific T cell line and 3 of 4 T cell clones. The T cell line/clones all responded strongly to PLP (139-151) in in vitro proliferative assays. Line SPL and all of the clones show strong proliferative response to the whole PLP molecule and to PLP (139-151).