产品
编 号：F121001
分子式：C17H19N2NaO6S
分子量：402.4
分子式：C17H19N2NaO6S
分子量：402.4
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
50mg
询价
询价
结构图
CAS No: 132-92-3
产品详情
生物活性：
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation.
体内研究：
Methicillin sodium salt (42.5和85 mg/kg；im 4 time daily；for 21 day or till sunpledant death) 对抗白细胞中的肠球菌。 Methicillin sodium salt (400 mg/kg；腹腔注射；once) 比对照组更好地存活感染小鼠。 甲氧西林钠盐 (400 mg/kg；ih once) 防止感染小鼠死亡。Animal Model:White New Zealand rabbits, weighing 2.0 to 3.0 kg
Dosage:42.5 and 85 mg/kg
Administration:Intramuscular injection; 42.5 and 85 mg/kg four times daily; for 21 days or till spontaneous death
Result:Inhibited enterococcus at 24 hours with a half-live of 1.1 h, but showed no statisticalsignificance to rabbits.
Animal Model:Mice with 5-7 X 108 S. aureus
Dosage:400 mg/kg
Administration:Intraperitoneal injection; 400 mg/kg; once
Result:Showed a survival rate of 30.5%, higher than compared group with a survival rate of 6.9%.
Animal Model:Mice with 5-7 X 108 S. aureus
Dosage:400 mg/kg
Administration:Subcutaneous injection; 400 mg/kg; once
Result:Suppressed large abscesses developed in mice, and also prevented mice from death.
体外研究：
Methicillin sodium salt (100 μg/mL；18 小时) 杀死 S. aureus 在细胞内培养 18 小时后。
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation.
体内研究：
Methicillin sodium salt (42.5和85 mg/kg；im 4 time daily；for 21 day or till sunpledant death) 对抗白细胞中的肠球菌。 Methicillin sodium salt (400 mg/kg；腹腔注射；once) 比对照组更好地存活感染小鼠。 甲氧西林钠盐 (400 mg/kg；ih once) 防止感染小鼠死亡。Animal Model:White New Zealand rabbits, weighing 2.0 to 3.0 kg
Dosage:42.5 and 85 mg/kg
Administration:Intramuscular injection; 42.5 and 85 mg/kg four times daily; for 21 days or till spontaneous death
Result:Inhibited enterococcus at 24 hours with a half-live of 1.1 h, but showed no statisticalsignificance to rabbits.
Animal Model:Mice with 5-7 X 108 S. aureus
Dosage:400 mg/kg
Administration:Intraperitoneal injection; 400 mg/kg; once
Result:Showed a survival rate of 30.5%, higher than compared group with a survival rate of 6.9%.
Animal Model:Mice with 5-7 X 108 S. aureus
Dosage:400 mg/kg
Administration:Subcutaneous injection; 400 mg/kg; once
Result:Suppressed large abscesses developed in mice, and also prevented mice from death.
体外研究：
Methicillin sodium salt (100 μg/mL；18 小时) 杀死 S. aureus 在细胞内培养 18 小时后。
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