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编 号:F122236
分子式:C28H23ClF3N7O2
分子量:581.98
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Debio 0617B, a multi-kinase inhibitor, reduces maintenance and self-renewal of primary human AML CD34+?stem/progenitor cells. Debio 0617B has a unique profile targeting key kinases upstream of STAT3/STAT5 signaling such as JAK, SRC, ABL, and class III/V receptor tyrosine kinases (TKs). Debio 0617B has documented efficacy in STAT3-driven solid tumors.
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