产品
编 号：F125017
分子式：C17H21NO4
分子量：303.35
分子式：C17H21NO4
分子量：303.35
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 13392-18-2
产品详情
生物活性：
Fenoterol (Th-1165), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research.
体内研究：
Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.Animal Model:Male C57BL/6J mice (6 weeks old) with neuropathy
Dosage:0.7 mg/kg
Administration:Intraperitoneal injection; twice a day; for 3 weeks
Result:Alleviated neuropathic allodynia during chronic treatment.
体外研究：
Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.
Fenoterol (Th-1165), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research.
体内研究：
Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.Animal Model:Male C57BL/6J mice (6 weeks old) with neuropathy
Dosage:0.7 mg/kg
Administration:Intraperitoneal injection; twice a day; for 3 weeks
Result:Alleviated neuropathic allodynia during chronic treatment.
体外研究：
Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.
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